McDonald's Address: 3853 Portola Pkwy, Irvine, CA 92602 Phone: (714) 505-3300 Hours: Mon: 4am-2am Tue: 4am-2am Wed: 4am-2am Thu: 4am-2am Fri: 4am-2am Sat: 4am-2am Sun: 4am-2am Restaurants Other Businesses: International Coffe and Tea at 5653 Alton Pkwy, Irvine, CA 92618 Koba Tofu Grill at 4501 Campus Dr, Irvine, CA 92612 Ameci Pizza and Pasta at 18068 Culver Dr, Irvine, CA 92612 McCormick at 2000 Main Street, Irvine, CA 92614 Gatten Sushi at 4517 Campus Dr, Irvine, CA 92612